Anti-BRMS-1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

BRMS-1

Immunogen :

A synthetic peptide of human BRMS-1

Synonym :

breast cancer metastasis-suppressor 1

Isotype :

IgG

Gene ID :

25855

Clone No :

Swiss Port :

Q9HCU9

Molecular weight :

28kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Cow

Application :

IHC

Recommended dilution :

IHC 1:200-600.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.