PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
KIF5BImmunogen :
A synthetic peptide of human KIF5BSynonym :
HEL-S-61;KINH;KNS;KNS1;UKHC;kinesin-1 heavy chainIsotype :
IgGGene ID :
3799Clone No :
Swiss Port :
P33176Molecular weight :
110kDaPurification :
Affinity purificationReactivity :
HumanApplication :
WB IHCRecommended dilution :
WB 1:5000-8000. IHC 1:50-200.Subcellular location :
Cytoplasm Cell membraneStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).RELATED PRODUCTS
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REFERENCE LIBRARY
No data