Anti-KIF5B Polyclonal Antibody

No :   K107451P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

KIF5B

Immunogen :

A synthetic peptide of human KIF5B

Synonym :

HEL-S-61;KINH;KNS;KNS1;UKHC;kinesin-1 heavy chain

Isotype :

IgG

Gene ID :

3799

Clone No :

Swiss Port :

P33176

Molecular weight :

110kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB IHC

Recommended dilution :

WB 1:5000-8000. IHC 1:50-200.

Subcellular location :

Cytoplasm Cell membrane

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity).
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REFERENCE LIBRARY
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