Anti-PTHLH Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PTHLH

Immunogen :

Recombinant protein of human PTHLH

Synonym :

HHM; Humoral hypercalcemia of malignancy; MGC14611; Osteostatin; PaRathyroid hormone like hormone; PaRathyroid hormone like protein; PaRathyroid hormone like related protein; PaRathyroid like protein; PLP; PTH related protein; PTHR; PTHRP;

Isotype :

IgG

Gene ID :

5744

Clone No :

Swiss Port :

P12272

Molecular weight :

20/24kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm? Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a member of the paRathyroid hormone family. This hormone, via its receptor, PTHR1, regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. It is responsible for most cases of humoral hypercalcemia of malignancy, and mutations in this gene are associated with brachydactyly type E2 (BDE2). Alternatively spliced transcript variants have been found for this gene. There is also evidence for alternative translation initiation from non-AUG (CUG and GUG) start sites, downstream of the initiator AUG codon, resulting in nuclear forms of this hormone.