Anti-EFNB1/2/3 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

EFNB1/2/3

Immunogen :

A synthetic peptide of human EFNB1/2/3

Synonym :

CFND;CFNS;EFB1;EFL3;EPLG2;Elk-L;LERK2;ephrin-B1

Isotype :

IgG

Gene ID :

1947/1948/1949

Clone No :

Swiss Port :

P98172/P52799/Q15768

Molecular weight :

36/37/38kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells. Shows high affinity for the receptor tyrosine kinase EPHB1/ELK. Can also bind EPHB2 and EPHB3. Binds to, and induces collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons.