Anti-CYSLTR1 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CYSLTR1

Immunogen :

A synthetic peptide of human CYSLTR1

Synonym :

CYSLT1;CYSLT1R;CYSLTR;HMTMF81;cysteinyl leukotriene receptor 1

Isotype :

IgG

Gene ID :

10800

Clone No :

Swiss Port :

Q9Y271

Molecular weight :

38kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Receptor for cysteinyl leukotrienes mediating bronchoconstriction of individuals with and without asthma. Stimulation by LTD4 results in the contraction and proliferation of smooth muscle, edema, eosinophil migration and damage to the mucus layer in the lung. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4.