Anti-GLRB Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

GLRB

Immunogen :

A synthetic peptide of human GLRB

Synonym :

Glycine receptor 58 kDa subunit;Glycine receptor beta;Glycine receptor subunit beta;Glycine receptor, beta subunit;OTTHUMP00000220896;OTTHUMP00000220897;

Isotype :

IgG

Gene ID :

2743

Clone No :

Swiss Port :

P48167

Molecular weight :

35/56kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Glycine receptors are ligand-gated chloride channels. GLRB does not form ligand-gated ion channels by itself, but is part of heteromeric ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Heteropentameric channels composed of GLRB and GLRA1 are activated by lower glycine levels than homopentameric GLRA. Plays an important role in the down-regulation of neuronal excitability. Contributes to the generation of inhibitory postsynaptic currents.