PRODUCT DESCRIPTION
Species :
CanineAssay Type :
Solid Phase Sandwich ELISASensitivity :
0.1 pg/mlDetection Range :
0.2-900 pg/mlAssay Length :
2-2.5hSample Type :
Whole BloodLong Name :
Interleukin 8Synonyms :
CXCL8; Chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine ligand 8; GCP-1; GCP1; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; IL8; Interleukin-8Background :
Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.RELATED PRODUCTS
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REFERENCE LIBRARY
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