Canine IL-8/CXCL8 Elisa Kit

No :   SEKC-0003
Size :   
Quantity :   
PRODUCT DESCRIPTION

Species :

Canine

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

0.1 pg/ml

Detection Range :

0.2-900 pg/ml

Assay Length :

2-2.5h

Sample Type :

Whole Blood

Long Name :

Interleukin 8

Synonyms :

CXCL8; Chemokine (C-X-C motif) ligand 8; C-X-C motif chemokine ligand 8; GCP-1; GCP1; LECT; LUCT; LYNAP; MDNCF; MONAP; NAF; NAP-1; NAP1; IL8; Interleukin-8

Background :

Interleukin-8 (IL-8), also known as CXCL8, is a chemokine that is upregulated at sites of inflammation where it promotes neutrophil infiltration and activation. IL-8 can form homodimers and heterodimers with CXCL4/PF4. Its bioactivity is regulated by proteolytic truncations, citrullination, and the decoy receptor DARC. IL-8 signals through CXCR1/IL-8 RA, which is also used by CXCL6, and through CXCR2/IL-8 RB, which is used by multiple CXC chemokines. IL-8 also binds to Serpin A1/alpha-1 Antitrypsin which prevents IL-8 interaction with CXCR1.
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