Bovine COX-2 Elisa Kit

Product Description

Species: Bovine
Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 18 pg/ml
Detection Range: 93-6000 pg/ml
Assay Length: 2-2.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Long Name: Cyclooxygenase 2
Synonyms: PTGS2; COX-2; COX2; GRIPGHS; PGG/HS; PGHS-2; PHS-2; hCox-2; Prostaglandin-endoperoxide synthase 2
Background: Cyclooxygenase (COX), also known as prostaglandin G/H synthase, is a membrane bound enzyme partly responsible for the catalysis of prostanoid synthesis. COX is expressed as at least three different isoforms. COX-1 is constitutively expressed and thought to regulate a number of 'housekeeping' functions such as vascular hemostasis, renal blood flow, and glomerular function. COX-2 expression is tightly regulated and induced by inflammatory mediators such as growth factors, cytokines, and endotoxin. COX-3 appears to be much more strictly regulated spatially and is observed in greatest abundance in cerebral cortex.
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