PRODUCT DESCRIPTION
Species :
MouseAssay Type :
Solid Phase Sandwich ELISASensitivity :
20pg/mlDetection Range :
39.1-2,500 pg/mlAssay Length :
3.5hSample Type :
Serum; Plasma; Cell culture supernatant.Long Name :
Growth Arrest Specific Protein 6Synonyms :
AXLLG; AXSF; AXL Stimulatory Factor; GAS6; Growth arrest specific 6; AXL receptor tyrosine kinase ligand;Background :
Gas6 (Growth Arrest Specific 6) is a secreted protein that contains an extensively gamma-carboxylated N-terminal Gla domain and is dependent upon vitamin K for activity. Gas6 signals through the receptors Axl, Dtk/Tyro3, and Mer and is inhibited by shed soluble forms of Axl and Mer. Gas6 protects cells from stress-induced apoptosis and promotes phagocytosis of apoptotic cell debris, promotes platelet activation but inhibits inflammatory cytokine production, and inhibits VEGF-induced angiogenesis, and regulates tumor cell invasiveness.RELATED PRODUCTS
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REFERENCE LIBRARY
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