Mouse Cystatin C Elisa Kit

Species :

Mouse

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

30 pg/ml

Detection Range :

125.0-8,000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Cystatin C

Synonyms :

ARMD11; bA218C14.4 (cystatin C); CST3; Cystatin 3; Cystatin C (amyloid angiopathy and cerebral hemorrhage); Gamma-trace; MGC117328; Neuroendocrine basic polypeptide; Post-gamma-globulin

Background :

Cystatin C is a secreted cysteine protease inhibitor that inhibits Cathepsins B, H, K, L, and S. Cystatin C serum concentration correlates closely to the glomerular filtration rate (GFR); elevated levels are associated with coronary artery and cardiovascular disease risk. Dysregulation of Cystatin C can modulate tumor growth and metastasis. In humans, the L68Q variant forms dimers and oligomers more easily than wild type protein and is the cause for hereditary Cystatin C amyloid angiopathy.