Human PD-L1/B7-H1 Elisa Kit

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

70 pg/ml

Detection Range :

156-10，000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Programmed Death-1

Synonyms :

CD279 antigen;CD279;hPD-1;PD-1;PD1hPD-l;PDCD1;Programmed cell death protein 1;Protein PD-1;SLEB2

Background :

PD-1 (Programmed Death-1 receptor) is a key regulator of the threshold of immune response and peripheral immune tolerance. It is expressed on activated T cells, B cells, monocytes, and dendritic cells and binds to PD-L1 or PD-L2. PD-1 ligation induces co-inhibitory signals in T cells promoting their apoptosis, anergy, and functional exhaustion. Blockade of the PD-1: PD-L1 interaction enhances anti-tumor immunity and shows potential for improving cancer immunotherapy.