Human EMMPRIN/CD147 Elisa Kit


Product Description

Species: Human
Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 3 pg/ml
Detection Range: 6.25-400 pg/ml
Assay Length: 3.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Long Name: Extracellular Matrix Metalloproteinase Inducer
Synonyms: BSG; 5F7; CD147; EMMPRIN; OK; M6; TCSF; EMPRIN
Background: The name EMMPRIN reflects this proteins extracellular metalloproteinase inducer activity. It is a cell surface protein with two extracellular Ig domains, a transmembrane domain, and a cytoplasmic domain. Its expression is often elevated in human tumor cells, which in turn promotes MMP-1, MMP-2 and MMP-3 production in melanoma cells and MMP-2 and MMP-9 production in breast cancer cells. It interacts with several types of molecules such as integrins, caveolin-1 and MCT1. TRA-1-85 is an epitope within EMMPRIN.
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REFERENCE LIBRARY

No:SEKH-0356
Size: