Human TF Elisa Kit

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

7 pg/ml

Detection Range :

15.6-1,000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Transferrin

Synonyms :

TF; Siderophilin; Serotransferrin; Beta-1 metal-binding globulin; PRO1557; PRO2086;

Background :

Transferrin, also known as serotransferrin and siderophilin, is an 80 kDa secreted glycoprotein that binds two Fe (3+) ions, transporting them from sites of absorption and heme degradation to those of storage and utilization. It is a member of the Transferrin family of proteins. Human Transferrin is synthesized as a 698 amino acid (aa) precursor that contains a 19 aa signal sequence and a 679 aa mature chain. The mature chain consists of two Transferrin-like domains, two high-affinity iron binding sites, one potential site for O-linked glycosylation, and two potential sites for N-linked glycosylation. Human Transferrin is 73% aa identical to mouse and rat Transferrin.