PRODUCT DESCRIPTION
Species :
HumanAssay Type :
Solid Phase Sandwich ELISASensitivity :
15 pg/mlDetection Range :
31.2-2,000 pg/mlAssay Length :
3.5hSample Type :
Serum; Plasma; Cell culture supernatant.Long Name :
TNF-like ligand 1ASynonyms :
TNFSF15; TL1; TL1A; VEGI; VEGI192A; Vascular endothelial growth inhibitor; TNLG1B; TNF superfamily member 15Background :
TL1A is a type II transmembrane protein belonging to the TNF superfamily and has been designated TNF superfamily member 15 (TNFSF15). TL1A is predominantly expressed in endothelial cells and its expression is inducible by TNF-alpha and IL-1alpha. TL1A binds with high affinity to death receptor 3 (DR3), now known as TNFRSF25. Depending on the cell context, ligation of DR3 by TL1A can trigger one of two signaling pathways, activation of the transcription factor NF-kB, or activation of caspases and apoptosis.RELATED PRODUCTS
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REFERENCE LIBRARY
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