Human MIS/AMH Elisa Kit

No :   SEKH-0252
Size :   
Quantity :   
PRODUCT DESCRIPTION

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

40 pg/ml

Detection Range :

78-5,000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Mullerian-inhibiting Substance/Anti-Mullerian Hormone

Synonyms :

AMH; MIF; MIS; Muellerian hormone;

Background :

Mullerian inhibiting substance (MIS), also named anti-M?llerian hormone (AMH), is a tissue-specific TGF-beta superfamily growth factor. Its expression is restricted to Sertoli cells of fetal and postnatal testis, and to granulosa cells of postnatal ovary. MIS is synthesized and secreted as a disulfide-linked homodimeric propeptide. Proteolytic cleavage is required to separate the N-terminal proregion from the C-terminal bioactive peptide. Both fragments remain associated in a non-covalent complex. The C-terminal sequence forms a cysteine knot via seven canonical cysteine residues found in TGF-beta superfamily members.
RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data