Human DMP1 Elisa Kit

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

80 pg/ml

Detection Range :

156-10,000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Dentin matrix acidic phosphoprotein 1

Synonyms :

DMP1; ARHP; ARHR; DMP-1; Dentin matrix acidic phosphoprotein 1

Background :

DMP-1 is a member of the SIBLING (small integrin-binding ligand, N-linked glycoprotein) family of ECM molecules. It is produced by osteoblasts and is found both intracellularly and extracellularly. Intracellularly, it exists in the nucleus where it acts as a transcriptional regulator. Following osteoblast activation, DMP-1 undergoes Ca2+-mediated phosphorylation, which induces its secretion into the ECM. There, it participates in mineralized matrix formation.