PRODUCT DESCRIPTION
Species :
HumanAssay Type :
Solid Phase Sandwich ELISASensitivity :
80 pg/mlDetection Range :
156-10,000 pg/mlAssay Length :
3.5hSample Type :
Serum; Plasma; Cell culture supernatant.Long Name :
Dentin matrix acidic phosphoprotein 1Synonyms :
DMP1; ARHP; ARHR; DMP-1; Dentin matrix acidic phosphoprotein 1Background :
DMP-1 is a member of the SIBLING (small integrin-binding ligand, N-linked glycoprotein) family of ECM molecules. It is produced by osteoblasts and is found both intracellularly and extracellularly. Intracellularly, it exists in the nucleus where it acts as a transcriptional regulator. Following osteoblast activation, DMP-1 undergoes Ca2+-mediated phosphorylation, which induces its secretion into the ECM. There, it participates in mineralized matrix formation.RELATED PRODUCTS
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REFERENCE LIBRARY
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