Human LAB7-1/CD80 Elisa Kit

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

30 pg/ml

Detection Range :

62.5-4,000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Cluster of Differentiation 80

Synonyms :

CD80; B7; B7-1; B7.1; BB1; CD28LG; CD28LG1; LAB7; CD80 molecule

Background :

Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4[5][6] (for attenuation of regulation and cellular disassociation). CD80 works in tandem with CD86 to prime T cells.