Human CD19 Elisa Kit

No :   SEKH-0121
Size :   
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PRODUCT DESCRIPTION

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

0.11 ng/ml

Detection Range :

0.234-30 ng/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Cluster of Differentiation 19

Synonyms :

CD19; B4; CVID3; CD19 molecule

Background :

B-lymphocyte antigen CD19, also known as CD19 molecule (Cluster of Differentiation 19), B-Lymphocyte Surface Antigen B4, T-Cell Surface Antigen Leu-12 and CVID3 is a transmembrane protein that in humans is encoded by the gene CD19. In humans, CD19 is expressed in all B lineage cells, except for plasma cells, and in follicular dendritic cells. CD19 plays two major roles in human B cells. It acts as an adaptor protein to recruit cytoplasmic signaling proteins to the membrane and it works within the CD19/CD21 complex to decrease the threshold for B cell receptor signaling pathways. Due to its presence on all B cells, it is a biomarker for B lymphocyte development, lymphoma diagnosis and can be utilized as a target for leukemia immunotherapies.
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