Human BD-4 Elisa Kit

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

0.8 pg/ml

Detection Range :

1.56-100 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Beta-defensin 104

Synonyms :

BD-4; DEFB-4; DEFB104; DEFB4; hBD-4; defensin; beta 4; DEFB104A; defensin beta 104A;

Background :

Beta-defensin 104 is a protein that in humans is encoded by the DEFB104A gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 104, DEFB104A and DEFB104B, in head-to-head orientation. This gene, DEFB104A, represents the more centromeric copy.