Human IL-37 Elisa Kit

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

15 pg/ml

Detection Range :

31.25-2,000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Interleukin 37

Synonyms :

IL37; FIL1; FIL1(ZETA); FIL1Z; IL-1F7; IL-1H; IL-1H4; IL-1RP1; IL-37; IL1F7; IL1H4; IL1RP1; Interleukin 37

Background :

Human interleukin 37, also named IL-1F7, FIL1 zeta, IL-1H4, and IL-1rp1, belongs to the IL-1 cytokine family. With the exception of IL-18 that maps to human chromosome 11, all IL-1 family members map to the same cluster on human chromosome 2. Mouse IL-37 has not been reported, but human IL-37 is active on mouse cells. Five isoforms (IL-37a through e) are generated through alternative exon usage and have distinct expression profiles. Like IL-1 alpha, IL-1 beta and IL-18, all of the IL-37 variants lack a typical signal peptide.