Anti-HEY2 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

HEY2

Immunogen :

A synthetic peptide of human HEY2

Synonym :

HEY2;CHF1;GRIDLOCK;GRL;HERP1;HESR2;HRT2;bHLHb32;hairy/enhancer-of-split related with YRPW motif protein 2

Isotype :

IgG

Gene ID :

23493

Clone No :

Swiss Port :

Q9UBP5

Molecular weight :

35kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.