Anti-CLDN7 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CLDN7

Immunogen :

A synthetic peptide of human CLDN7

Synonym :

CEPTRL2;CLDN-7;CPETRL2;Hs.84359;claudin-1;claudin-7

Isotype :

IgG

Gene ID :

1366

Clone No :

Swiss Port :

O95471

Molecular weight :

17/22kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Cell membrane

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.