Anti-OXT Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

OXT

Immunogen :

A synthetic peptide of Human OXT

Synonym :

OT;OT-NPI;OXT-NPI;oxytocin-neurophysin 1

Isotype :

IgG

Gene ID :

5020

Clone No :

Swiss Port :

P01178

Molecular weight :

12kDa

Purification :

Affinity purification

Reactivity :

Human Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Secreted

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.