Anti-TNNC1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TNNC1

Immunogen :

Recombinant protein of human TNNC1

Synonym :

CMD1Z, TN C, TNC, TNNC, TNNC1, troponin C type 1 (slow)

Isotype :

IgG

Gene ID :

7134

Clone No :

Swiss Port :

P63316

Molecular weight :

18kDa

Purification :

Affinity purification

Reactivity :

Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Cytoplasm?

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z.