Anti-PTK2 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PTK2

Immunogen :

Recombinant protein of human PTK2

Synonym :

PTK2;FADK;FAK;FAK1;FRNK;PPP1R71;p125FAK;pp125FAK;focal adhesion kinase 1

Isotype :

IgG

Gene ID :

5747

Clone No :

Swiss Port :

Q05397

Molecular weight :

40/49/63/99/121/114/119kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:5000-8000. IHC 1:100-300.

Subcellular location :

Cell junction Cell membrane Cytoplasm Cytoplasmic side Nucleus Peripheral membrane protein cell cortex centrosome cytoskeleton focal adhesion microtubule organizing center

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.