Anti-eIF4E Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

eIF4E

Immunogen :

A synthetic peptide of human eIF4E

Synonym :

AUTS19;CBP;EIF4E1;EIF4EL1;EIF4F;eIF-4E;eukaryotic translation initiation factor 4E

Isotype :

IgG

Gene ID :

1977

Clone No :

Swiss Port :

P06730

Molecular weight :

25/29kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Cow Rabbit

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm Secreted

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants.