Anti-PSPN Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PSPN

Immunogen :

A synthetic peptide of human PSPN

Synonym :

PSP;Persephin

Isotype :

IgG

Gene ID :

5623

Clone No :

Swiss Port :

O60542

Molecular weight :

17kDa

Purification :

Affinity purification

Reactivity :

Human Rat

Application :

WB IHC

Recommended dilution :

WB 1:8000-12000. IHC 1:25-100.

Subcellular location :

Secreted

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo.