Anti-CFL1 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CFL1

Immunogen :

Recombinant protein of human CFL1

Synonym :

CFL;HEL-S-15;CFL1;Cofilin 1;cofilin 1 (non muscle);Cofilin;non muscle isoform;p18

Isotype :

IgG

Gene ID :

1072

Clone No :

Swiss Port :

P23528

Molecular weight :

19kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:10000-15000. IHC 1:50-200.

Subcellular location :

Cell membrane Cell projection Cytoplasm Cytoskeleton Membrane Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.