Anti-TNFSF18 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TNFSF18

Immunogen :

A synthetic peptide of human TNFSF18

Synonym :

TNFSF18;AITRL;GITRL;TL6;TNLG2A;hGITRL;TNF superfamily member 18

Isotype :

IgG

Gene ID :

8995

Clone No :

Swiss Port :

Q9UNG2

Molecular weight :

23kDa

Purification :

Affinity purification

Reactivity :

Mouse

Application :

WB

Recommended dilution :

WB 1:8000-12000.

Subcellular location :

Cell membrane Single-pass type II membrane protein

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1. Promotes leukocyte adhesion to endothelial cells. Regulates migration of monocytes from the splenic reservoir to sites of inflammation (By similarity).