Anti-Smad4 Polyclonal Antibody

No :   K106653P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

Smad4

Immunogen :

A synthetic peptide of human Smad4

Synonym :

DPC4;hSMAD4;JIP;MAD homolog 4;MADH4;Mothers against DPP homolog 4;SMAD 4;SMAD family member 4;SMAD4;MYHRS

Isotype :

IgG

Gene ID :

4089

Clone No :

Swiss Port :

Q13485

Molecular weight :

60kDa

Purification :

Affinity purification

Reactivity :

Mouse

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8.
RELATED PRODUCTS
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REFERENCE LIBRARY
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