PRODUCT DESCRIPTION
Conjugation :
UnconjugateHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
Smad4Immunogen :
A synthetic peptide of human Smad4Synonym :
DPC4;hSMAD4;JIP;MAD homolog 4;MADH4;Mothers against DPP homolog 4;SMAD 4;SMAD family member 4;SMAD4;MYHRSIsotype :
IgGGene ID :
4089Clone No :
Swiss Port :
Q13485Molecular weight :
60kDaPurification :
Affinity purificationReactivity :
MouseApplication :
IHCRecommended dilution :
IHC 1:50-200.Subcellular location :
Cytoplasm NucleusStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
In muscle physiology, plays a central role in the balance between atrophy and hypertrophy. When recruited by MSTN, promotes atrophy response via phosphorylated SMAD2/4. MSTN decrease causes SMAD4 release and subsequent recruitment by the BMP pathway to promote hypertrophy via phosphorylated SMAD1/5/8.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data