Anti-VIP Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

VIP

Immunogen :

A synthetic peptide of human VIP

Synonym :

VIP peptides;PHV-42;PHM-27;Vasoactive intestinal polypeptide;Peptide histidine valine 42

Isotype :

IgG

Gene ID :

7432

Clone No :

Swiss Port :

P01282

Molecular weight :

19kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:2000-5000. IHC 1:50-200.

Subcellular location :

Cytoplasm Nucleus Cell membrane

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

VIP(Vasoactive Intestinal peptide) is a 28-amino acid peptide structurally related tosecretin. It was originally isolated from intestinal extracts and shown to be a potent vasodilator. Subsequent work demonstrated that VIP is very widely distributed in the peripheral and central nervous systems, and probably should not be considered a true GI hormone. A huge number of biological effects have been attributed to VIP. With respect to the digestive system, VIP seems to induce smooth muscle relaxation (lower esophageal sphincter, stomach, gallbladder), stimulate secretion of water into pancreatic juice and bile, and cause inhibition of gastric acid secretion and absorption from the intestinal lumen.