Anti-Nephrin Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

Nephrin

Immunogen :

A synthetic peptide of human Nephrin

Synonym :

CNF;nephrin;NPHN;NPHS1;

Isotype :

IgG

Gene ID :

4868

Clone No :

Swiss Port :

O60500

Molecular weight :

100kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:3000.

Subcellular location :

Cell membrane Single-pass type I membrane protein

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease. Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss. Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2.