Anti-PRKACA/PRKACB Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PRKACA/PRKACB

Immunogen :

A synthetic peptide of human PKAalpha+beta

Synonym :

PPKACA;PKACA;PPNAD4;PKA C-alph;PKA C-beta;PKACB;PRKACA/PRKACB;PKAalpha+beta

Isotype :

IgG

Gene ID :

5566/5567

Clone No :

Swiss Port :

P17612/P22694

Molecular weight :

41kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:2000-5000. IHC 1:50-200.

Subcellular location :

Cell membrane Cytoplasm Membrane Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis.