Anti-FINC Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

FINC

Immunogen :

A synthetic peptide of human FINC

Synonym :

Fn1;FN;Fibronectin;FNZ;GFND;GFND2

Isotype :

IgG

Gene ID :

14286

Clone No :

Swiss Port :

P11276

Molecular weight :

272kDa

Purification :

Affinity purification

Reactivity :

Mouse Rat

Application :

WB

Recommended dilution :

WB 1:3000.

Subcellular location :

Extracellular matrix

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts.Anastellin binds fibronectin and induces fibril formation. This fibronectin polymer, named superfibronectin, exhibits enhanced adhesive properties. Both anastellin and superfibronectin inhibit tumor growth, angiogenesis and metastasis. Anastellin activates p38 MAPK and inhibits lysophospholipid signaling.