Human CTSB(Cathepsin B) ELISA KIT

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

62.5pg/mL

Detection Range :

125-8000pg/mL

Assay Length :

3h15min

Sample Type :

Serum, plasma, Cell culture supernatant

Long Name :

Ovarian carcinoma antigen CA125

Synonyms :

APP secretase; APPS; Cathepsin B; Cathepsin B1; CPSBamyloid precursor protein secretase; CTSB; cysteine protease; EC 3.4.22; EC 3.4.22.1

Background :

Cathepsin B is the first described member of the family of lysosomal cysteine proteases. Cathepsin B possesses both endopeptidase and exopeptidase activities, in the latter case acting as a peptidyl-dipeptidase. It is known to process a number of proteins, including pro and active caspases, prorenin and SLPI. Cathepsin B is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme.