Anti-Neuropilin 1 Monoclonal Antibody

Conjugation :

Unconjugation

Host :

Mouse

Clonality :

Monoclonal antibody

Gene symbol :

Neuropilin 1

Immunogen :

Recombinant protein of human Neuropilin 1

Synonym :

BDCA4, CD304, neuropilin 1, NRP, NRP1, VEGF165R

Isotype :

IgG1

Gene ID :

8829

Clone No :

Swiss Port :

O14786

Molecular weight :

103kDa

Purification :

Affinity purification

Reactivity :

Human pig

Application :

WB FC IF ELISA

Recommended dilution :

WB : 1:1000-1:6000. IF : 1:50-1:500. FCM :0.2米g/Test.

Subcellular location :

Cell membrane Secreted Single-pass type I membrane protein

Storage :

Store at -20⊥. Avoid freeze / thaw cycles.

Background :

Neuropilin-1 (NRP1) is a a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.