Anti-CRISPLD2 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CRISPLD2

Immunogen :

Recombinant protein of human CRISPLD2

Synonym :

CRISPLD2;CRISP11;LCRISP2;LGL1

Isotype :

IgG

Gene ID :

83716

Clone No :

Swiss Port :

Q9H0B8

Molecular weight :

13/17/42/51/56kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Predicted:Bovine

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Secreted

Storage :

Store at -20℃. Avoid freeze / thaw cycles.

Background :

Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins that may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP proteins are highly expressed in the mammalian reproductive tract and in the venom secretory ducts of some reptiles. CRISP-11 (cysteine-rich secretory protein 11), also known as cysteine-rich secretory protein LCCL domain-containing 2 (CRISPLD2 or LCRISP2), is a 497 amino acid protein containing 2 LCCL domains, which are thought to function as autonomous folding domains used to construct modular proteins through exon shuffling. Serum concentrations of CRISP-11 have been shown to be an indicator of a patient＊s exposure to lipopolysaccahride (LPS), the immunostimulatory component of Gram-negative bacteria, and can determine one＊s sensitivity to it.