PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
CLCN7Immunogen :
Recombinant protein of human CLCN7Synonym :
ClC-7Isotype :
IgGGene ID :
1186Clone No :
Swiss Port :
P51798Molecular weight :
86/89kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
IHCRecommended dilution :
IHC 1:50-200.Subcellular location :
CytoplasmStorage :
Store at -20℃. Avoid freeze / thaw cycles.Background :
Slowly voltage-gated channel mediating the exchange of chloride ions against protons (PubMed:18449189, PubMed:21527911). Functions as antiporter and contributes to the acidification of the lysosome lumen and may be involved in maintaining lysosomal pH (PubMed:18449189, PubMed:21527911, PubMed:31155284). The CLC channel family contains both chloride channels and proton-coupled anion transporters that exchange chloride or another anion for protons (By similarity). The presence of conserved gating glutamate residues is typical for family members that function as antiporters (By similarity).RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data