Anti-SARS-CoV/CoV-2 Spike S1 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SARS-CoV/CoV-2 Spike S1

Immunogen :

Recombinant protein of SARS-CoV/CoV-2 Spike S1

Synonym :

Isotype :

IgG

Gene ID :

1489668

Clone No :

Swiss Port :

P59594

Molecular weight :

139kDa

Purification :

Affinity purification

Reactivity :

SARS-CoV Spike S1 SARS-CoV-2 Spike S1 SARS-CoV-2 Spike RBD

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Storage :

Store at -20℃. Avoid freeze / thaw cycles.

Background :

Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 and CLEC4M/DC-SIGNR receptors and internalization of the virus into the endosomes of the host cell induces conformational changes in the S glycoprotein. Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes.