Mouse BST1/CD157 ELISA KIT

Species :

Mouse

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

15.625pg/ml

Detection Range :

31.25-2000pg/ml

Assay Length :

3.5h

Sample Type :

Serum, plasma, Cell culture supernatant

Long Name :

bone marrow stromal cell antigen 1 (BST-1)/CD157

Synonyms :

114/A10 Matched ELISA Antibody Pair Set, Mouse; A530073F09 Matched ELISA Antibody Pair Set, Mouse; BP-3 Matched ELISA Antibody Pair Set, Mouse; Bp3 Matched ELISA Antibody Pair Set, Mouse; Bsta1 Matched ELISA Antibody Pair Set, Mouse; CD157 Matched ELISA Antibody Pair Set, Mouse; Ly65 Matched ELISA Antibody Pair Set, Mouse

Background :

The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD157, also known as ADP-ribosyl cyclase 2, is an ectoenzyme sharing several characteristics with ADP-ribosyl cyclase CD38. CD157 was originally identified as a bone marrow stromal cell molecule (BST-1) with a glycosylphosphatidylinositol (GPI) anchor to bind to the cell surface. CD157 is prevalently expressed by cells of the myeloid lineage. CD157 could act as a receptor with signal transduction capability. Further, it regulates calcium homeostasis and promotes polarization in neutrophils and mediates superoxide (O2?) production in the human U937 myeloid line.