Mouse BMP-5 ELISA KIT

No :   SEKM-0184
Size :   
Quantity :   
PRODUCT DESCRIPTION

Species :

Mouse

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

46.875pg/ml

Detection Range :

93.75-6000pg/ml

Assay Length :

3.5h

Sample Type :

Serum, plasma, Cell culture supernatant

Long Name :

Bone morphogenetic protein 5

Synonyms :

BMP5; BMP-5; bone morphogenetic protein 5; MGC34244

Background :

Bone morphogenetic protein 5 (BMP5) is a protein that in Mouses is encoded by the BMP5 gene and is a member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce bone and cartilage development.BMP5 may play a role in certain cancers. Like other BMP's BMP5 is inhibited by chordin and noggin. It is expressed in the trabecular meshwork and optic nerve head and may have a role in the development and normal function. It is also expressed in the lung and liver. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis.This gene is differentially regulated during the formation of various tumors.
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