Anti-PAK3 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PAK3

Immunogen :

A synthetic peptide of human PAK3

Synonym :

ARA; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; bPAK; beta-PAK

Isotype :

IgG

Gene ID :

5063

Clone No :

Swiss Port :

O75914

Molecular weight :

61/62/63/65kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human Mouse Predicted: Chimpanzee Xenopus laevis

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Apr 2016]