Anti-SRGN Polyclonal Antibody

No :   K110499P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SRGN

Immunogen :

Recombinant protein of human SRGN

Synonym :

PPG;PRG;PRG1;serglycin

Isotype :

IgG

Gene ID :

5552

Clone No :

Swiss Port :

P10124

Molecular weight :

18kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human

Application :

WB

Recommended dilution :

WB 1:500-2000.

Subcellular location :

Cytoplasm

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

Plays a role in formation of mast cell secretory granules and mediates storage of various compounds in secretory vesicles. Required for storage of some proteases in both connective tissue and mucosal mast cells and for storage of granzyme B in T-lymphocytes. Plays a role in localizing neutrophil elastase in azurophil granules of neutrophils. Mediates processing of MMP2. Plays a role in cytotoxic cell granule-mediated apoptosis by forming a complex with granzyme B which is delivered to cells by perforin to induce apoptosis. Regulates the secretion of TNF-alpha and may also regulate protease secretion. Inhibits bone mineralization.
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