Anti-RNF182 Polyclonal Antibody

No :   K110218P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

RNF182

Immunogen :

A synthetic peptide of human RNF182

Synonym :

E3 ubiquitin-protein ligase RNF182;RING finger protein 182;RING-type E3 ubiquitin transferase RNF182;

Isotype :

IgG

Gene ID :

221687

Clone No :

Swiss Port :

Q8N6D2

Molecular weight :

27kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514).
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