PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
RNF182Immunogen :
A synthetic peptide of human RNF182Synonym :
E3 ubiquitin-protein ligase RNF182;RING finger protein 182;RING-type E3 ubiquitin transferase RNF182;Isotype :
IgGGene ID :
221687Clone No :
Swiss Port :
Q8N6D2Molecular weight :
27kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
WB IHCRecommended dilution :
WB 1:1000-3000. IHC 1:50-200.Subcellular location :
CytoplasmStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514).RELATED PRODUCTS
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REFERENCE LIBRARY
No data