Anti-KPNA6 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

KPNA6

Immunogen :

Recombinant protein of human KPNA6

Synonym :

Importin subunit alpha-7;Karyopherin subunit alpha-6;IPOA7;

Isotype :

IgG

Gene ID :

23633

Clone No :

Swiss Port :

O60684

Molecular weight :

60kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Nucleus Cytoplasm

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.