Anti-RFK Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

RFK

Immunogen :

A synthetic peptide ofHuman RFK

Synonym :

Riboflavin kinase;ATP:riboflavin 5'-phosphotransferase;Flavokinase;

Isotype :

IgG

Gene ID :

55312

Clone No :

Swiss Port :

Q969G6

Molecular weight :

18kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Secreted

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Catalyzes the phosphorylation of riboflavin (vitamin B2) to form flavin-mononucleotide (FMN), hence rate-limiting enzyme in the synthesis of FAD. Essential for TNF-induced reactive oxygen species (ROS) production. Through its interaction with both TNFRSF1A and CYBA, physically and functionally couples TNFRSF1A to NADPH oxidase. TNF-activation of RFK may enhance the incorporation of FAD in NADPH oxidase, a critical step for the assembly and activation of NADPH oxidase.