Anti-FAIM3 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

FAIM3

Immunogen :

Recombinant protein of Human FAIM3

Synonym :

FAIM3, TOSO

Isotype :

IgG

Gene ID :

9214

Clone No :

Swiss Port :

O60667

Molecular weight :

31/34/43kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Secreted

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.