PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
CSTAImmunogen :
Recombinant protein of human CSTASynonym :
STF1;STFAIsotype :
IgGGene ID :
1475Clone No :
Swiss Port :
P01040Molecular weight :
11kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
IHCRecommended dilution :
IHC 1:50-200.Subcellular location :
CytoplasmStorage :
Store at -20°C. Avoid freeze / thaw cycles.Background :
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data