Anti-PRKAA1 Monoclonal Antibody

Conjugation :

Unconjugation

Host :

Mouse

Clonality :

Monoclonal Antibody

Gene symbol :

PRKAA1

Immunogen :

Recombinant Protein

Synonym :

PRKAA1;AMPK;AMPKa1

Isotype :

IgG1

Gene ID :

5562

Clone No :

9G3

Swiss Port :

Q13131

Molecular weight :

64/66kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:100-300.

Subcellular location :

Cytoplasm

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.