Anti-TBP Monoclonal Antibody

Conjugation :

Unconjugation

Host :

Mouse

Clonality :

Monoclonal Antibody

Gene symbol :

TBP

Immunogen :

Recombinant Protein

Synonym :

GTF2D1;TF2D;TFIID;TATA Binding Protein

Isotype :

IgG1

Gene ID :

6908

Clone No :

4H2

Swiss Port :

P20226

Molecular weight :

38/36kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.